I don't think you are quite grasping the carburetor concept yet.
That mikuni has a main jet and an idle circuit. The main jet is essentially a straw stuck down in the bowl. It's what feeds the engine the fuel when it's not idling. Inside the main jet is a needle. It comes from the top and is driven by the throttle slide. It is responsible for fuel mixture above idle, up to about 3/4 throttle. It essentially changes the size of the main jet for partial throttle mixture. It's adjustable via a little e-clip. Move the e-clip down, more rich. Up, more lean. The needle is important for throttle response. It may die off if its too far off. There is also an air bypass tube that you can see from the opening of the carb. That also has a little straw going in to the bowl, but the mixture is controlled by the screw. So you have an idle screw mixture screw and an idle speed screw. That's it. Do not over tighten the idle mixture screw! It's an itty bitty needle valve inside an aluminum bore. Damage the seat and your carb is done for.
So there are a few things that could go wrong. Also, the spark plug can tell you the story about how lean or rich it is. On a 4 stroke engine, lean will surge (the speed goes up, down, up, down) and rich will bog (engine sounds labored). On a 2 stroke, it's almost backwards. Rich will sputter like a machine gun (and sound about 1/2 speed) and lean will bog down.
If the spark plug is looking like you just drug it out of a coal mine, then lean it up some. If it's not getting a little soot, you need to fatten up the mix.
Start with a fresh plug, and try moving the slide needle before messing with the main jet.
I also just remembered about the float. If your bowl isn't level, you will have such a hard time with it. Does it dribble fuel out the inlet when the engine is off? On the flip side, maybe the float isn't letting enough fuel in the bowl and the jet can only suck air in?