It really depends on what throttle position your carb is at when you experience 4 stroking.
It is a very common mis-understanding that one should tune a carburetor for problems encountered during a particular RPM range. The truth of the matter is carburetors meter fuel in relation to throttle position and the air flowing through them, not engine speed.
The needle controls fuel flow from just off idle to 3/4 throttle.
The fuel jet controls fuel from 3/4 to full throttle.
(There is more to it, but that is just the basics that usually lets one tune these simple carburetors.)
There is overlap in the control circuits so when you adjust one it will have a slight affect on the other.
You need to determine at what position you are having issues at and tune accordingly.
The easiest way is to put a piece of tape on the throttle grip housing and another piece on the throttle grip. With the grip at the idle (closed position) mark a line on the grip tape to act as a reference arrow. Also directly across from this reference arrow put another mark on the housing tape to indicate closed position. Now hold the throttle grip at the full throttle position and put a mark on the housing tape to indicate full throttle position. Now put equally spaced marks in between the marks you made on the housing tape to show 1/4 throttle, 1/2 throttle, and 3/4 throttle. When you ride the bike and the engine acts up you now can glance down at this home made indicator and easily and accurately see where the throttle position is. No guess work or hunches needed.
This makes tuning the carburetor easy as you can tune the exact fuel circuit that needs tuning, not another circuit that you think might be the problem.
When you are done, remove the tape.