The only frame failures I've seen are those with the front motor mount attached by drilling through the frame - which makes me uneasy of course as I was forced to do this
I suspect that much of this is due to the structural weakening caused by a hole in such a critical area, combined with a 2 stroke that isn't running as well as it could (4stroking & additional vibration) as well as loose mounts/attempts to reduce felt vibration with "soft" motor mounts.
Add to that the stock "rag joint" type rear sprocket mounting - guaranteed only to be offset, leading to a almost imperceptible yet constant and serious "wrenching" of the engine to the drive side and this all adds up as contributing factors.
Yeah - I've given this a little thought as it's my ass on the line lol
Yet, my build seems to be holding up well. I've addressed all the above except the sprocket mount (soon to change). I would say that an in-frame mount done
properly without drilling the frame, "soft" mounts, or some of the strange offset exhaust clamp style mounts done in desperation would be the safest, most balanced, and effective method of engine placement.
There's a reason that motorcycles have their engines where they do lol - no offense to the rack-mount crowd, I've had my fair share and loved 'em, but the odd balance and inability to have a cargo rack (minor issue, but annoying) have made me go with the in-frame style with no reservations.
All in all - I wouldn't blame the in-frame style for any failures, I'd blame poor mount techniques - an issue that would plague rack mounts too I bet