I'm going to bump this old thread because I did some research on the issue of disc brakes and quick release rims prior to installing them on a bike that originally had rim brakes.
One point that was not brought up here is something called, 'Lawyer Lips'. No, it has nothing to do with attorneys.
A lawyer lip is the indented or convex portion of the front fork/dropout, that is designed to keep the axle from falling out unless the nuts or quick release is extremely loose. Loose enough that any amount of common sense would tell the rider there's a problem before the wheel falls off. I don't have the data in front of me but early bikes did not have lawyer lips but all bikes made or sold in the U.S for some years have had this required improvement to fork design. I have an 80s vintage Roadmaster that did not have the feature so the law must have been passed after it was built.
Goat Herder posted some links a while back, to studies done on the issue of quick release (QR) rims and disc brakes. In the article they explain the potential for a wheel to be pulled out of the dropout by the forces applied on it by a disc. They go on to say that bikes with Lawyer Lips are pretty much immune to this danger.
And while we're on the subject of disc brakes, if you've never had them and then install them, you'll never go back to rim brakes again. Guaranteed.
Tom