roger mentioned raising exhaust and lowering intake, as well as cleaning up the transfers. All that in addition to ramping the piston. You should really only do one or the other unless you want a really high power band (my bike is tuned for 8500 rpm, and trust me, it's no faster than my new one out of the box, but the new one uses more gas, is louder, and takes off way faster.
The one tuned for 8500 RPM only has raised exhaust, reed valves and intake window on the piston & 4 3/8" holes next to the wrist pin to reduce weight (and give me a much larger harmonic sweet spot), an SBP pipe attached via flex pipe (internal ridges disrupt exhaust flow though, go with as smooth a pipe as possible). This motor's been through **** though as I learned how to tweak and I learned several things:
#1, exhaust tuned length. It's set for 8500 RPM (about 36" or so), but the ridges in the flex pipe disrupt flow and leak like crazy (my white shoes are now pitch black). Needs to be re-done with either copper piping or bending/welding handlebars
#2, the RSE Reed valves are much, MUCH too small for these engines, 50cc high performance reed engines use huge reeds with quad valves. Get the arrows if you don't go custom.
#3, not enough compression with the stock head (~80psi), needs to be shaved down to nearly flat with the aluminum heatsink or use an aftermarket head.
#4, lighter pistons are better. the lighter you make the whole assembly, the less vibrations you will suffer from. My piston weighs about 96 grams (stock is 108g iirc). You can purchase a titanium wrist pin for about $12 that will cut off 8 grams of weight.
#5 the transfers are terrible, TERRIBLE angles. This is quite possibly the biggest loss of power from an out-of-the-box motor. If you want instant power, fix the angles.
#6 the intake manifold and port (non GT5a engines) are much too small. high performance 50cc engines use 25mm carbs, the NT carb out of the box has a 14mm venturi with a 3/4" (19mm) mounting point. A 19mm dellorto PHBG clone can be had for about $44 and comes with all mounting hardware. Get yourself a GT5a cylinder (REQUIRED! you will need the bolt spacing) and weld up a 1" O.D., 3/4" I.D. intake manifold [the largest possible on our engines without extensive modification]. Stock intake is 3/4" O.D., 1/2" I.D. so even the 14mm stock carbs are bigger than the manifold they're attaching to.
#7 Performance vs Reliability. If you want raw performance, use the stock CDI, it's tuned for maximum power every stroke. If you want to save your bearings (which you should have replaced with american or japanese 6202 bearings anyway), get the jag CDI (or lightning?), it retards at high RPM, putting less pressure on the rod and bearings because the 'bang' wont be as strong when the piston starts descending. Has almost no effect on vibrations, that has to do with the weight you're throwing around.
#8 Get a proper piston. The Hoca Minarelli has been found to fit, but needs cast iron rings or better cylinder plating, is already ported for reeds and weighs just as much as the stock piston. The rings will seal properly, retaining pressure and being thinner, reduce wear and sliding resistance. Get a titanium wrist pin to reduce vibrations