My 2 cents, which is just that......I personally would never try to cram a HF 420cc into anything less than a tandem, for several reasons. The main reason would be as Lurker has suggested....the weight and power of a stock HF 420 and a more practical application of a HF 212cc with a few mods.
I've seen Scott's frames (Silverstate) and a few of his builds and I just don't see a 420cc being a practical or whatever option for a build in that frame without some modifications.
Do what you wanna do though, cuz that's what I do
I do like the electric starters on the HF 420's.....you almost need one for that brute